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Organ-Specific and Tissue-Specific Manifestation

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Introduction

The particular parts including organs, tissues, and cells are influenced by microorganisms we call organ and tissue explicit signs. At the point when the microorganisms influence the whole organ, for example, lungs or kidneys, it is known as an organ-explicit indication. At the point when the whole tissue is influenced by the organisms, it is known as a tissue-explicit indication. 


Microorganisms influence certain parts, including cells and organ tissues. We call this the organ and tissue explicit sign.


After a certain amount of time, when microorganisms influence the entire organ, for example, kidneys and lungs, it is called Organ-Explicit Indication.


Furthermore, when the organisms influence the entire tissue, it is observed to be Tissue-Explicit Indication.


Organ-Specific Manifestation

The microorganisms entering our body move and start to increase in a particular organ. Hence, various organs are home to different kinds of microbial species. If we talk about an example,

  • Mycobacterium tuberculosis is a microscopic organism that causes tuberculosis in organisms. 

  • Salmonella enters through the mouth (when we consume tainted food or water) and transports to the gut lining. 

  • HIV infection enters the body through our sexual organs and spread throughout our body.

  • The malarial parasites enter our liver and spread throughout our red blood platelets.

We can see the sign of the sickness by observing the tissue or organ it targets. When we realize a slight aggregation in a particular organ or tissue in our body, this generally means it is the beginning of an infection.


Tissue-Specific Manifestation

Just like the organs, the tissues get infected by the microorganisms and get harmed by them. The seriousness of the ailments depends on the number of microorganisms that affect that certain tissue. 


Our body’s safe framework does keep us aware of the quantity of the organisms in the body, and whenever this insusceptible framework gets harmed because of a dangerous infection like HIV, the body is no longer able to fight these contaminations.


Whenever the microorganisms harm the entire tissue or cell in a particular illness, our resistant framework tries its best to fight against them. This is known as aggravation.

  • For example, if the microorganisms harm our lungs, manifestations of sickness would be things like shortness of breath. 

This manifestation usually causes a thing called Irritation, where a resulting growth of territory due to synthetics like histamine and hydroxytryptamine causing unfavorably susceptible responses cause this phenomenon.

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FAQs on Organ-Specific and Tissue-Specific Manifestation

1. How can we define Organ-Specific and Tissue-Specific manifestations of disease in brief?

Here are the brief definitions of both the different types of manifestations: 

Organic Specific Manifestations are diseases that are caused by a specific organ or organ system, which becomes the point of entry for that particular microbe.


An example can be Tuberculosis where the microbes enter through the nose and affect the lungs.


Tissue-Specific manifestations are diseases caused in different areas as the point of entry in the body. An example is Malaria where the target is the bloodstream and it slowly spreads throughout the body.

2. What is the major difference between Organic Specific and Tissue-Specific Manifestation?

The major difference between the Organic Specific Manifestation and the Tissue-Specific Manifestation is the target of the attack, which means where the microorganisms attack the various tissues and organs in our body.


For example, in Tuberculosis, bacteria attack a specific organ which is the Lungs. Through the infected lungs, the disease then spreads throughout the human body.


In contrast, in Malaria, the infection spreads through the bloodstream. The infection-causing organism enters through the blood but then spreads throughout the body.

3. What symptoms do microorganisms cause to the Brain, Lungs, and Liver?

Microorganisms cause different types of symptoms to different organs:

  • In the Brain, Encephalitis causes different symptoms like decreased sensation, change in personality or behavior, vomiting, and fever.

  • In Lungs, microorganisms usually attack the lungs and can cause Tuberculosis and Pneumonia, their symptoms are cough, chest pain, prolonged fever.

  • In the Liver, the major disease that occurs is Jaundice caused by the Hepatitis Virus, its symptoms are high fever, loss of appetite, yellow pigmentation of the eye, and dark pigmentation of urine.

4. Is Corona an Organic Specific Manifestation or Tissue-Specific Manifestation?

Corona has major organ-specific manifestations that can mainly enter the human body through the nose and go towards the lungs. Lung involvement is the utmost common manifestation of Corona, which by entering the body also causes asymptomatic diseases like mild pneumonia to severe diseases like hypoxia, respiratory failure, and multi-organ failure that can be lethal.


According to the World Health Organization, Coronavirus Disease (COVID-19) is an infectious disease that is caused by the SARS-CoV-2 virus. The major symptom of this disease is mild to moderate respiratory illness.

5. How does Vedantu help the students in understanding the concept of Organic Specific Manifestation or Tissue-Specific Manifestation?

Here at Vedantu, we not only provide in-depth study material on this particular topic and other various vital biological concepts, but we also provide live learning where a student can understand essential concepts at their own pace. We also provide downloadable PDFs that a student can view on their different devices for offline use.


Vedantu’s frictionless flexibility throughout different devices and platforms makes it super helpful for students who want to clear their doubts and concepts and ace in their examinations.

6. The signs and symptoms of a disease will depend on the tissue or organ which the microbe targets justify the statement with two examples.

Every microorganism shows its effect on any particular tissue or organ after entering into the body. Thus, there is a change in the structure and function of that tissue or organ. For example, if the lungs are the targets, the symptoms will be cough and breathlessness. If the liver is the target, there will be jaundice. This is called Organ-specific manifestation.

7. Write A short note on organ-specific and tissue-specific Manifestations of Disease?

When the microbes affect the entire organ, such as lungs or kidneys, it is known as organ-specific manifestation. The microorganisms that enter the body travel to a specific organ and multiply there. Different microbes are at home in different parts of the body. For instance, Mycobacterium tuberculosis is the bacteria that cause tuberculosis.  When the entire tissue is affected by the microbes, it is called a tissue-specific manifestation. The immune system is also activated in response to the infections. The microorganisms enter into the tissues and damage them. The immune system recruits the disease-causing microbes and destroys them. This is known as inflammation.

8. The signs and symptoms of a disease will depend on the tissue or organ which the microbe targets justify the statement with two examples.

Every microorganism shows its effect on any particular tissue or organ after entering into the body. Thus, there is a change in the structure and function of that tissue or organ. For example, if the lungs are the targets, the symptoms will be cough and breathlessness. If the liver is the target, there will be jaundice. This is called Organ-specific manifestation.


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