Question

Allosteric sites on an enzyme are:
A. Those other than drug-active sites
B. Those which change the shape of active sites
C. Those which don't change the shape of active sites
D. All of the above

Answer 1

Hint: Enzymes are a kind of fluid that are produced by duct bearing exocrine glands. They are basically a body protein that plays the role of a catalyst in metabolic processes (such as food digestion).

Complete Answer
To find the correct answer to this question, we first need to dig a bit deeper into the concept and understand a few of the terminologies and workings of an enzyme.
Active sites: are the openings present on the substrate body through which an enzyme enters into it. It is specific for specific enzymes.
Following steps describe working of an enzyme:
1. Enzymes and substrates come together (that is, in each other's vicinity).
2. Enzyme enters into the substrate through its active site forming an enzyme-substrate complex that reduces reaction initiation energy.
3. Chemical reaction takes place between enzymes and substrates to form products. The product-enzyme complex formed. After completion of the reaction, the enzyme leaves the product to proceed alone for further reactions.
This clearly signifies that statements mentioned in both options A and B that are those other than drug-active sites and those which change the shape of active sites are correct.

Therefore, we can say that this question has two correct options, that is, A and B.

Note:
A few important terms need to be mentioned for a better understanding if the topic, such as:
Substrates: are compounds that are acted upon by an enzyme for further breakdown and conduction of metabolic processes.
Allosteric sites: are those sites that can be used to on/off or or modify the shape of the substrate, so that enzymes cannot detect it to act upon. This concept is highly used by various drugs for medical treatment.