Question

What are the two layers of the basement membrane, and what makes each layer?

Answer 1

Hint: More than one layer of cells lies on the basal lamina in stratified epithelium, which is subjected to mechanical and chemical stresses. Mechanical stresses are also important in wound healing because they allow cells to migrate towards the wound.

Complete answer:
The basement membrane (BM) is a fibrous matrix secreted by epithelial cells that is predominantly made up of glycoproteins, type IV collagen, and laminin. Basement membranes are a thick, sheetlike form of extracellular matrix (ECM) that surrounds muscle, fat, and Schwann cells and lies beneath epithelial and endothelial.

Basement membranes are a layer of tissue that separates and protects tissues from mechanical stress.The reticular lamina and the basal lamina are the two layers that make up the basement membrane.

The epithelium rests on top of a sheet of extracellular matrix secreted by epithelial cells called the basal lamina. Collagens, laminin (glycoprotein), perlecan (heparan sulphate glycoprotein), and entactin make up the basal lamina (glycoprotein). These proteins can interact with one another to form a crosslinked extracellular matrix.

The epithelium's reticular lamina is a thin extracellular layer that often lies under the basal lamina. Collagen and elastin are secreted by connective tissue fibroblasts in the reticular lamina.

Note: Basement membranes are thin sheet-like extracellular structures that form an anatomical barrier wherever cells meet connective tissues. They provide a substrate for organs and cells and relay important signals for the development of organs and for differentiation and maintenance of the tissue.