Question

Differentiate between the following based on what is given in the brackets.
Lymphocytes and Neutrophils (structure of nucleus).

Answer 1

Hint: Lymphocytes and neutrophils both are the types of Leukocytes (white blood corpuscles/WBCs). WBCs are colourless due to the lack of haemoglobin. They are almost invisible under the microscope unless they are stained. They possess nuclei and other cell organelles and can move in an amoeboid fashion.

Complete answer:
Following are the differences between lymphocytes and neutrophils based on the nucleus.

Lymphocytes	Neutrophils
Lymphocytes are small cells with round and large nuclei and little cytoplasm	Neutrophils are the most abundant WBCs cells with multi-lobulated nuclei.
The nucleus of the lymphocyte is stained dark purple and almost fills the cell. They have dark-purple stained condensed chromatin.	Neutrophils have a characteristic multilobed nucleus, with 3 to 5 lobes joined by slender strands of genetic material.
The nucleolus does not disappear at maturity.	The nucleolus disappears as the neutrophil matures.
Lymphocytes are agranulocytes. They do not contain granules in their cytoplasm.	Neutrophils are granulocytes. They contain granules in their cytoplasm.
They exist in two major forms, namely B and T- lymphocytes and are responsible for immune responses of the body.	They are phagocytic. They commonly squeeze between the cells of the capillary walls and wander through the intercellular spaces. From here they move to infected areas of the body. They engulf and digest disease-causing bacteria.

Note: Leukocytes are 6000- 8000 per cubic millimetre of blood. Among them, 20-25% are Lymphocytes and 60-65 % are neutrophils. The lifespan of lymphocytes is about a few days, or months or even years. The lifespan of neutrophils is about 4 to 8 hours in the blood, 4 to 5 days in the tissue.