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In which part of the body, are argentaffin cells found?
A. Oesophagus
B. Mainly in the Duodenum
C. Only in Rectum
D. In all parts of the alimentary canal, but predominantly in the small intestine

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Answer
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Hint: Argentaffin cells are related to a part of an organ of the gastrointestinal tract where digestion is completed. It is the first region of the small intestine where various digestive juices mixed together.

Complete answer:
The argentaffin cells are mainly found in the duodenal part of the small intestine. These are located among the epithelial cells lining the crypts of Lieberkuhn. It is an enteroendocrine cell that secretes enzymes in the digestive tract.
The function of Argentaffin Cells:
-It is responsible for the secretion of serotonin and histamine which act as vasoconstrictor and vasodilator respectively.
-Help in regulating the rhythmic contraction and relaxation of muscles in the alimentary canal
Layers of the gastrointestinal tract:
-Mucosa: This layer is the innermost layer. Villi and rugae are formed by this layer in different parts of the alimentary canal.
-Submucosa: Formed of loose connective tissue and contains nerves, blood, and lymph.
-Muscularis: Composed of smooth muscles, having an inner circular and outer longitudinal layer.
-Serosa: Outermost layer and composed of this mesothelium and some connective tissue.
Several types of glandular cells are present along the lining of the alimentary canal, they are:
-Mucous Neck Cells- Secrete mucus which is alkaline
-Peptic or Zymogenic Cells- Secrete proenzymes pepsinogen and prorennin (in infants)
-Oxyntic or Parietal Cells- Secrete HCL and Castle Intrinsic factor which is needed for vitamin B12 absorption.
-G Cells- Secrete hormone gastrin, which increases gastric motility.
-D Cells- Secrete somatostatin, which inhibits gastric motility

So, the correct answer is, “ Mainly in the duodenum”.

Note:
Argentaffin cells are also referred to as enterochromaffin cells and Kulchitsky cells and these names should not be confused with other cell types. They are only responsible for the secretion of hormones and not any digestive juices.
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