Question

Podocytes are cells present in the
(a)Cortex of nephron
(b)The inner wall of bowman’s capsule
(c)The outer wall of bowman’s capsule
(d)Well of glomerular capillaries

Answer 1

Hint:The podocytes have long foot processes called pedicels which help infiltration of blood. The pedicels of podocytes wrap themselves around the glomerular capillaries and help infiltration of blood.

Complete answer:Podocytes are cells in the inner wall Bowman's capsule in the nephrons of the kidney that wrap around capillaries of the glomerulus.

Additional information:
>Podocytes are found in the inner wall of the Bowman's capsules in the nephrons of the kidney.
>The foot processes of the podocytes are called pedicels that give podocytes their name, the pedicels extend from the podocytes wrap themselves around the capillaries of the glomerulus to form the filtration slits.
>There are many coated vesicles and coated pits along the base of the podocytes which show a high rate of vehicular traffic.
>Podocytes have a well-developed endoplasmic reticulum and a large Golgi apparatus, suggestive of a large potential for protein synthesis and post-translational alterations.
>There is also a large number of lysosomal components seen in these cells, suggesting a high endocytic activity.
>The functions of the podocytes are: the pedicels of the podocyte increase the surface area of the bowman’s capsule enabling efficient ultrafiltration, podocytes secrete, and maintain the basement membrane, podocytes also maintain the regulation of glomerular filtration rate.

                                                        

So, the correct answer is “The inner wall of bowman’s capsule”.

Note: A Loss of the foot processes i.e pedicels of the podocytes (i.e., obliteration of podocyte) is a sign of the minimal change disease, which has hence sometimes been referred to as foot process disease. Disruption or destruction of the filtration slits of the podocytes can result in proteinuria, where massive amounts of protein are lost from the blood through urine, or haematuria, where RBCs are lost through urine.