Answer
Verified
405k+ views
Hint: Grignard reagents are organometallic compounds having a metal and an organic group along with a halogen, with the formula, RMgX, where R is any alkyl group, Mg is magnesium and X is halogen. They undergo additional reactions with carbonyl groups. Epoxides are tricyclic compounds having one carbonyl group.
Complete answer:
Grignard reagents are highly basic organometallic compounds. They have the tendency to react with any species that donates a proton. Grignard reagents are capable of generating a nucleophile, which can react with electrophiles in addition to reactions. On the other hand, epoxides are tricyclic compounds having 2 carbon and 1 oxygen atoms. They, when undergoes addition with Grignard reagents, leads to the ring opening of the epoxides.
The reaction of epoxide with Grignard reagents leads to the formation of primary alcohols, with two carbons more than the length, due to the ring opening. The reaction of epoxide with Grignard reagents is:
Epoxide opens as the electrophile is generated by the addition of the alkyl group by Grignard reagent on epoxide. This when subjected to acidic conditions leads to the formation of a primary alcohol.
Hence, reaction of epoxides with Grignard reagent generates primary alcohols.
Note:
Epoxides are also called ethylene oxides. The reaction follows the mechanism of nucleophilic substitution, which is ${{S}_{N}}^{2}$ type. The strong basic condition of the Grignard reagent is responsible for the opening of the ring of the epoxides. The acid workup is the final step in the reaction of epoxides. Apart from reaction with epoxides, Grignard also reacts with aldehydes, ketones, acid chlorides, etc. compounds with a carbonyl group.
Complete answer:
Grignard reagents are highly basic organometallic compounds. They have the tendency to react with any species that donates a proton. Grignard reagents are capable of generating a nucleophile, which can react with electrophiles in addition to reactions. On the other hand, epoxides are tricyclic compounds having 2 carbon and 1 oxygen atoms. They, when undergoes addition with Grignard reagents, leads to the ring opening of the epoxides.
The reaction of epoxide with Grignard reagents leads to the formation of primary alcohols, with two carbons more than the length, due to the ring opening. The reaction of epoxide with Grignard reagents is:
Epoxide opens as the electrophile is generated by the addition of the alkyl group by Grignard reagent on epoxide. This when subjected to acidic conditions leads to the formation of a primary alcohol.
Hence, reaction of epoxides with Grignard reagent generates primary alcohols.
Note:
Epoxides are also called ethylene oxides. The reaction follows the mechanism of nucleophilic substitution, which is ${{S}_{N}}^{2}$ type. The strong basic condition of the Grignard reagent is responsible for the opening of the ring of the epoxides. The acid workup is the final step in the reaction of epoxides. Apart from reaction with epoxides, Grignard also reacts with aldehydes, ketones, acid chlorides, etc. compounds with a carbonyl group.
Recently Updated Pages
10 Examples of Evaporation in Daily Life with Explanations
10 Examples of Diffusion in Everyday Life
1 g of dry green algae absorb 47 times 10 3 moles of class 11 chemistry CBSE
What happens when dilute hydrochloric acid is added class 10 chemistry JEE_Main
What is the meaning of celestial class 10 social science CBSE
What causes groundwater depletion How can it be re class 10 chemistry CBSE
Trending doubts
Fill the blanks with the suitable prepositions 1 The class 9 english CBSE
Which are the Top 10 Largest Countries of the World?
How do you graph the function fx 4x class 9 maths CBSE
Distinguish between the following Ferrous and nonferrous class 9 social science CBSE
The term ISWM refers to A Integrated Solid Waste Machine class 10 social science CBSE
The Equation xxx + 2 is Satisfied when x is Equal to Class 10 Maths
Difference between Prokaryotic cell and Eukaryotic class 11 biology CBSE
Which is the longest day and shortest night in the class 11 sst CBSE
In a democracy the final decisionmaking power rests class 11 social science CBSE