Question

Which of the following hormones stimulates the pancreas to secrete enzymes?
A.Enterocrinin
B.CCK-PZ
C.Gastrin
D.Secretin

Answer 1

Hint Neuroendocrine cells which are located in the mucosa of the upper small intestine released a special type of hormones. The food molecules rich in proteins and fats stimulate the cells to produce this hormone. This hormone stimulates pancreatic secretion by two mechanisms.
Complete Step-by-step answer: Digestive system constitutes the gastrointestinal tract and other organs that assist to break down food into simpler substances so that body can easily absorb them. The digestive system breaks down food into nutrients with the help of a variety of enzymes and hormones.
The pancreas is located in the abdomen. It is a part of the digestive system and plays a crucial role in the digestion of food. Apart from these, it regulates blood sugar.
The enteroendocrine cells which are located in the duodenum secrete and synthesized cholecystokinin hormone. Cholecystokinin is also known as CCK-PZ. Its secretion is strongly stimulated by the presence of partially digested proteins and fats in the small intestine. As chyme floods into the small intestine, cholecystokinin is released into the blood and binds to receptors on pancreatic acinar cells, ordering them to secrete large quantities of digestive enzymes.
Cholecystokinin acts on the pancreas and gall bladder and stimulates the secretion of pancreatic enzymes from the pancreas and also bile from the gall bladder. These pancreatic enzymes assist in the breakdown of fats, proteins, and carbohydrates. Normally pancreas secretes approximately eight cups of pancreatic juice to the duodenum on a daily basis. This fluid contains a pancreatic enzyme that helps in digestion. Lipase, protease, and amylase are the three types of pancreatic enzymes. Lipase helps in breaking down fats while protease and amylase help in the breakdown of protein and carbohydrates respectively.
Hence the correct answer is option B. CCK-PZ.
Note: If the pancreatic enzyme is not produced by the pancreas sufficiently, digestion is affected, and external enzyme supplements have to be provided. Thus, medical practitioners prescribe digestive enzymes, including pancreatic enzymes, to patients who have conditions that cause poor digestion.