Question

Which of the following statement is incorrect about oxidative deoxy carboxylation
A. It takes place in the mitochondrial matrix
B. Two molecules of NADH are produced by one molecule of pyruvate
C. Pyruvate dehydrogenase is used as the catalyst in the reaction
D. Two molecules of NADH produced by two molecules of pyruvate

Answer 1

Hint: Anaerobic respiration is the process during which oxidation of organic substances within the presence of oxygen and releases $CO_{2}$ and water. Anaerobic respiration is most typical in higher organisms.

Complete answer: Aerobic respiration takes place within the mitochondria and alSo, the final product of glycolysis, pyruvate is transported from the cytoplasm to the mitochondria.
When pyruvate enters within the mitochondrial matrix it undergoes oxidative decarboxylation by a posh set of reactions catalysed by pyruvate dehydrogenase. The reactions catalysed by pyruvate dehydrogenase require the participation of several coenzymes, including $NAD^{+}$ and coenzyme.
In this process, two molecules of NADH are produced from the metabolism of two molecules of acid and it ends up in a net gain of 6 ATP molecules. (2NADH = 6ATP)
The acetyl CoA then enters a cyclic pathway, tricarboxylic acid cycle and more commonly referred to as Krebs’ cycle after the scientist Hans Krebs’ first elucidated it.
Krebs cycle starts with the reaction between the acetyl moiety of acetyl-CoA and alSo, the four-carbon dicarboxylic acid oxaloacetate, forming a six=carbon trio xylic acid, citrate. This reaction is catalysed by the enzyme citrate synthase and a molecule of CoA is released.

Note: In Krebs’s cycle, two molecules of $FADH_{2}$ and two molecules of GTP are formed. One molecule of $FADH_{2}$ generates 2 molecules of ATP, therefore the net gain of ATP is going to be 4 molecules. The process of formation of acetyl CoA from acid is termed a link reaction or gateway reaction between glycolysis and Krebs’s cycle. Question: Which of the following statement is incorrect about oxidative deoxy carboxylation