
Who discovered the Genetic Code?
A. Nierenberg
B. Khorana
C. Ochoa
D. Crick
Answer
568.5k+ views
Hint: Genetic Code is the term we use for the way that the four bases of DNA- the A, C, G, and T - are hung together such that the cell apparatus, the ribosome, can understand them and transform them into a protein. In the hereditary code, every three nucleotides straight consider a trio and code for a solitary amino corrosive. The genetic code is referred to as universal.
Complete answer: Marshall Nirenberg and Heinrich Matthaei unraveled hereditary code by combining polypeptide utilizing fake mRNA conveying a particular succession of bases.
1. They hatched manufactured polyuridylate, poly(U), GTP, ATP, E. coli extricate and a blend of the 20 amino acids in 20 distinct cylinders containing an alternate radioactively marked amino corrosive.
2. The poly(U) mRNA has numerous progressive UUU trios and consequently, the resultant polypeptide ought to contain just the amino corrosive encoded by the trio UUU.
3. It was reasoned that the trio codon UUU encodes a phenylalanine. Khorana utilized a similar way to deal with uncovering that polycytidylic, encodes a polypeptide containing just proline and polyadenylate encodes polylysine. Khorana thinks back how the finding that qualities are nucleic acids made way for his work on disentangling.
4. Crick in a joint effort with A. Lately Crick, in a joint effort with S. Brenner, has focused more on organic chemistry and hereditary qualities prompting thoughts regarding protein amalgamation (the adaptor hypothesis), and the hereditary code, and specifically to chip away at acridine-type freaks.
So, the correct answer is “Option A”.
Note: The hereditary code is the arrangement of rules utilized by living cells to interpret data encoded inside hereditary material (DNA or mRNA successions of nucleotide trios, or codons) into proteins. Interpretation is cultivated by the ribosome, which joins amino acids in a request indicated by courier RNA (mRNA), utilizing move RNA (tRNA) particles to convey amino acids and to peruse the mRNA three nucleotides all at once.
Complete answer: Marshall Nirenberg and Heinrich Matthaei unraveled hereditary code by combining polypeptide utilizing fake mRNA conveying a particular succession of bases.
1. They hatched manufactured polyuridylate, poly(U), GTP, ATP, E. coli extricate and a blend of the 20 amino acids in 20 distinct cylinders containing an alternate radioactively marked amino corrosive.
2. The poly(U) mRNA has numerous progressive UUU trios and consequently, the resultant polypeptide ought to contain just the amino corrosive encoded by the trio UUU.
3. It was reasoned that the trio codon UUU encodes a phenylalanine. Khorana utilized a similar way to deal with uncovering that polycytidylic, encodes a polypeptide containing just proline and polyadenylate encodes polylysine. Khorana thinks back how the finding that qualities are nucleic acids made way for his work on disentangling.
4. Crick in a joint effort with A. Lately Crick, in a joint effort with S. Brenner, has focused more on organic chemistry and hereditary qualities prompting thoughts regarding protein amalgamation (the adaptor hypothesis), and the hereditary code, and specifically to chip away at acridine-type freaks.
So, the correct answer is “Option A”.
Note: The hereditary code is the arrangement of rules utilized by living cells to interpret data encoded inside hereditary material (DNA or mRNA successions of nucleotide trios, or codons) into proteins. Interpretation is cultivated by the ribosome, which joins amino acids in a request indicated by courier RNA (mRNA), utilizing move RNA (tRNA) particles to convey amino acids and to peruse the mRNA three nucleotides all at once.
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