
How to make anhydride from carboxylic acid?
Answer
445.2k+ views
1 likes
Hint: When a water molecule is removed from any acid molecule, the product that we get is known as an anhydride. In organic acid anhydride, there are two acyl groups (R-C=O) bonded to the same oxygen atom. Its generic structure is
Complete step-by-step answer: The anhydride obtained from carboxylic acid is one of the most common types of organic acid anhydride. It is also known as carboxylic anhydride. The molecular formula of carboxylic anhydride is .
Formation of acid anhydrides from carboxylic acid occurs when the carboxylic acid reacts with an acid chloride in the presence of a base.
Mechanism of synthesis of carboxylic anhydride from acid chloride:
- In the carboxylic acid synthesis, addition-elimination mechanism is followed.
- Chloride anion acts as a leaving group.
- First, a proton is extracted by the base from carboxylic acid and forms carboxylate anion.
- The negatively charged oxygen of the carboxylate anion attacks the carbonyl carbon of acyl chloride, which is electrophilic in nature, and forms a tetrahedral intermediate.
- Lastly, the tetrahedral intermediate eliminates the chloride anion to form acid anhydride.
Hence by adding acid anhydride to a carboxylic acid, in the presence of a strong base, acid anhydride can be obtained.
Note: While naming the acid anhydrides, it is important to note that in an unsymmetrical acid anhydride, both of the carboxylic acids reacted must be named before adding the word anhydride. Whereas in symmetrical acid anhydride, simply renaming the word "acid" to "anhydride" of the parent carboxylic acid would suffice.

Complete step-by-step answer: The anhydride obtained from carboxylic acid is one of the most common types of organic acid anhydride. It is also known as carboxylic anhydride. The molecular formula of carboxylic anhydride is
Formation of acid anhydrides from carboxylic acid occurs when the carboxylic acid reacts with an acid chloride in the presence of a base.

Mechanism of synthesis of carboxylic anhydride from acid chloride:

- In the carboxylic acid synthesis, addition-elimination mechanism is followed.
- Chloride anion
- First, a proton is extracted by the base from carboxylic acid and forms carboxylate anion.
- The negatively charged oxygen of the carboxylate anion attacks the carbonyl carbon of acyl chloride, which is electrophilic in nature, and forms a tetrahedral intermediate.
- Lastly, the tetrahedral intermediate eliminates the chloride anion to form acid anhydride.
Hence by adding acid anhydride to a carboxylic acid, in the presence of a strong base, acid anhydride can be obtained.
Note: While naming the acid anhydrides, it is important to note that in an unsymmetrical acid anhydride, both of the carboxylic acids reacted must be named before adding the word anhydride. Whereas in symmetrical acid anhydride, simply renaming the word "acid" to "anhydride" of the parent carboxylic acid would suffice.
Latest Vedantu courses for you
Grade 11 Science PCM | CBSE | SCHOOL | English
CBSE (2025-26)
School Full course for CBSE students
₹41,848 per year
Recently Updated Pages
Express the following as a fraction and simplify a class 7 maths CBSE

The length and width of a rectangle are in ratio of class 7 maths CBSE

The ratio of the income to the expenditure of a family class 7 maths CBSE

How do you write 025 million in scientific notatio class 7 maths CBSE

How do you convert 295 meters per second to kilometers class 7 maths CBSE

Write the following in Roman numerals 25819 class 7 maths CBSE

Trending doubts
Give 10 examples of unisexual and bisexual flowers

Draw a labelled sketch of the human eye class 12 physics CBSE

Differentiate between homogeneous and heterogeneous class 12 chemistry CBSE

Differentiate between insitu conservation and exsitu class 12 biology CBSE

What are the major means of transport Explain each class 12 social science CBSE

Franz thinks Will they make them sing in German even class 12 english CBSE
