Question

How many phosphodiester bonds are present in ATP?
(A) 3
(B) 2
(C) 1
(D) 0

Answer 1

Hint: DNA and RNA are the chain of a polynucleotide which are linked by the phosphodiester bonds. It is designed by the linkage between the 3' carbon atom of one sugar molecule and the 5' carbon atom of another. Two hydroxyl groups on the phosphate molecule bind to the 3’ and 5’ carbons on two dominant pentose sugars to form a bond.

Complete answer:
A phosphodiester bond exists when just two of the hydroxyl groups in phosphoric acid react with hydroxyl groups with other molecules to form two ester bonds. Phosphodiester bonds are crucial to all life on Earth as they assemble the backbone of the strands of nucleic acid.
For the phosphodiester bond to be formed and the nucleotides to be linked, the tri-phosphate or di-phosphate forms of the nucleotide building blocks are torn apart to give off energy needed to drive the enzyme-catalyzed reaction. When a single phosphate or two phosphates are known as pyrophosphates break away and catalyze the reaction, the phosphodiester bond is established. The phosphodiester connection between two ribonucleotides can be broken by alkaline hydrolysis, whereas the linkage between two deoxyribonucleotides is more stable under these conditions.
Option A- 3 :This option is not correct for the following question
Option B- 2: This option is also wrong.
Option C- 1: This option is also wrong
Option D- 0: ATP has three phosphates out of which one is directly connected to the ribose with phosphate ester bond and it is an insufficient energy bond. The bond between two phosphate groups is a phosphoanhydride bond which is supposed to be a high energy bond. According to this ATP has only two high energy bonds i.e., phosphoanhydride bond and no phosphodiester bond.

So, the correct answer is "0" phosphodiester bond.

Note: Adenosine triphosphate (ATP) is a nucleotide spent in cells as a coenzyme. It is often called the molecular unit of currency of cells. ATP conveyances chemical energy within cells for metabolism.