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What causes swelling of the lower limbs in patients suffering from filariasis?

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Answer
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Hint: The various threads like parasitic roundworms and their larvae obtained tropical filariasis disease. Mosquito bite transfers the disease through the larvae into the human body. headache, chills, and fever are the characteristics of the early stage of filariasis. Enlargement of the limbs and genitalia is the result of untreated filariasis at the appropriate time. “Brugia malayi” is the scientific name of the filariasis that is caused by the roundworm parasites.

Complete answer:
The disease is caused by the adult’s worms in the lymphatic vessels that present near the lymph nodes and cause local inflammation or distortion of the vessels. The surrounding tissues become enlarged in the advanced stage of the worms that obstruct the vessels. In the legs and genitalia blockage of the lymphatic system caused by the repeated inflammation. Due to the mosquito bites the lymphatic filariasis disease spreads out and travels to the lymphatic system which includes lymph vessels and lymph nodes.

Additional Information: -
The worm larvae migrate to the eyes due to the conjunctiva filariasis and onchocerciasis cause a type of blindness if untreated. Worms cause infection if symptoms vary depending on what type of parasitic but symptoms of all infections begin with the chills and headache mostly. Scrotum, legs, and pain in the arms, redness, and swelling are the main symptoms.

Note: Patient history, physical examination, and immune system in response to the infection screen by the blood specimens for the specific proteins produced inside the body, signs of the obstruction of the lymphatic, microfilariae that are found in the larvae and blood of the body. The treatment of diethylcarbamazine and albendazole used to treat filariasis.