Question

Haemophilia man marries a normal woman. Their offspring will be.
A. All normal
B. All haemophiliac
C. All boys haemophiliac
D. All girls haemophiliac

Answer 1

Hint: A mutation is a change in a DNA order. It can result from mistakes in DNA copying during cell division; it occurs due to exposure to ionizing radiation, chemicals called mutagens and due to infection caused by viruses.

Complete answer:
Firstly let's know what is Genetic disorder is.
It is a disease caused in whole or in part by a change in the DNA sequence away from the normal sequence. Genetic disorders can be caused by a mutation in one gene known as monogenic disorder, or by mutations in multiple genes known as multifactorial inheritance disorder.

Some of the genetic disorders are:
1. Cystic fibrosis
2. Down syndrome
3. Haemophilia
4. Klinefelter syndrome.

> Haemophilia: Haemophilia is an inherited genetic disorder that damages the body's ability to make blood clots, and this process needed to stop bleeding.
This results in people bleeding for a longer time after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain.

There are two main types of haemophilia:
- Haemophilia A is type of haemophilia which occurs due to low amounts of clotting factor VIII
- Haemophilia B is a type of haemophilia which occurs due to low levels of clotting factor IX.
Haemophilia is mainly caused due to the genetic mutation.
It is a recessive X linked.
X chromosome received from mother has the gene for normal blood clotting while X chromosome from her father has the gene for hemophilia. The gene from the mother is dominant.

Therefore, female heterozygous are always carriers.
When a haemophilic man marries a normal woman, produces carrier girls and normal boys which mean all their offspring will be normal.

Hence, The correct answer is option (A).

Note: Sickle cell anemia is one of a group of disorders known as sickle cell disease.
They are an inherited red blood cell disorder in which there aren't enough healthy red blood cells to carry oxygen throughout your body.
Treatment of sickle cell anemia is Blood transfusion.