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If groundwater is contaminated with excess of arsenic it causes ……………… disease.

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Answer
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Hint: It is a unique disease of the peripheral arterial system, characterized by severe arteriosclerosis. It is an endemic disease and found mainly in China. It happens due to the consumption of an elemental compound having Atomic number 33.

Complete answer:
Black foot is a disease of the vascular system which is characterized by long term exposure to arsenic. There are various ranges of symptoms that are observed, some of them are ischemia and pallor. The other symptoms include coldness or numbness in the extremities. Over the years the symptoms include, claudication and spontaneous amputation.
1. It is observed mainly in China- a province in Taiwan.
2. Long term exposure to arsenic through drinking water and contaminated food can lead to the cause of black-foot disease and skin lesions.
3. black -foot disease is a severe form of peripheral vascular disease in which the blood vessels in the lower limbs are damaged.
4. The effective preventive measure is the minimal use of arsenic affected water.
5. According to WHO, the clean water can be ensured in the following ways
i. Digging of deeper wells, because deeply dug wells are the least contaminated.
ii. Testing of arsenic levels in water by informed professionals
Iii. The use of arsenic removal systems in the household can also be a safer method.

So, the correct answer is, Black foot.

Note:
Disease caused due to nitrate is called methemoglobinemia. It is also called nitrate poisoning.
Disease caused due to fluoride is fluorosis or crippling disease.
Disease caused by mercury is called Minamata disease in which skin becomes pink and peels of.