Question

Which of the following genetic diseases shows criss-cross pattern of inheritance
A. Haemophilia and colour blindness
B. Haemophilia, colour blindness and hypertrichosis of ear
C. Albinism and sickle cell anaemia
D. Klinfilters syndrome and turner's syndrome

Answer 1

Hint: The transmission of a gene from a father to a daughter or from a mother to a son is known as criss-cross inheritance. Because the character is transferred to the second generation through the carrier of the first generation, this pattern of gene inheritance is also known as skip generations. Inheritance from a female or male parent is passed down through X-linked traits to the grandson or granddaughter through the offspring of opposite sex in criss-cross inheritance. Skip generation is another name for criss cross inheritance.

Complete answer:
Option A: The transmission of a gene from a mother to a son or a father to a daughter is known as criss-cross inheritance. Take a look at the X-chromosome link. Criss-cross inheritance is common for X-chromosome-linked recessive mutations. The recessive genes are inherited in the same way as the X chromosome. They are expressed in both hemizygous and homozygous males, but only in females. In humans, criss-cross inheritance can be seen. All of a red–green colorblind father's children are likely to be normal, whereas all of a colorblind mother's male children are likely to be impacted. Although their sons (grandsons' fathers) have normal vision, some of the male grandkids of color-blind grandfathers will be color-blind.
So, option A is correct.
Option B: Hypertrichosis pinnae auris is a Y-linked character, according to the literature. A number of studies have established that the trait is passed down from father to son, with any exceptions attributable to the gene's lack of penetrance or crossing over from the Y to X chromosome.
Sp option B is not correct.
Option C: Sickle cell anemia is an autosomal recessive disease, meaning that both copies of the gene in each cell carry mutations. The parents of a person with an autosomal recessive disorder each have one copy of the faulty gene, but they usually don't display any signs or symptoms of the disease.
Hence option C is not correct.
Option D: The extra X chromosome occurs as a result of either the mother's egg or the father's sperm carrying the extra X chromosome (an equal possibility of this happening in either), hence the chromosome pattern is XXY rather than XY after conception.
So, option D is not correct.

Therefore, Option A is the correct answer.

Note:
Mendelian disorder is a form of genetic disorder that affects people and is caused by changes in one gene or abnormalities in the genome. Such a disorder can be detected from birth and derived from family history through the use of a family tree. Pedigree analysis is the term for the analysis that is carried out as a result of this. Genetic illnesses can be inherited or not. Non-inheritable genetic disorders are produced by new mutations or changes in the DNA, whereas inheritable genetic illnesses are caused by new mutations or changes in the DNA.